Project
Site- and stage- specific chronic inflammation and fibrosis in Fuchs endothelial corneal dystrophy
Strain- and metabolism-dependent genetic variations of (lymph)angiogenesis: identification of candidates and influence on corneal wound healing
Personalized anti(lymph)angiogenic and immune modulatory therapies in high-risk corneal transplantation
Metabolic control of corneal hem- and (lymph)angiogenesis
The role of limbal mesenchymal stem cells in corneal (lymph)angiogenesis, inflammation and UV-induced pterygium pathogenesis
Thrombospondin-1 and NF-κB signaling in ocular graft-versus-host disease (GVHD)
Role of macrophage-dependent osmoprotective and hypoxic signal transduction in inflammatory corneal diseases
CD83-based immunomodulation in ocular surface inflammation such as dry eye
Variability and organ specificity of lymphatic vessel – dendritic cell interactions in the eye (allergic conjunctivitis)
Mitochondrial DNA at the interface between mitochondrial dysfunction and neuroinflammation in glaucoma
The lymphatic regulator SVEP1 in Schlemm´s canal function – a therapeutic target for glaucoma
In depth investigation of the molecular signalling mechanisms and cellular function of midkine, neuropilin-2 and sFLT1 in conjunctival and uveal melanoma
Tumor-microenvironmental alterations during pathogenesis and therapy of conjunctival melanoma
Galectins in the pathogenesis of retinal neovascular and inflammatory diseases
Translocator protein (TSPO)-induced ROS production by NADPH oxidases in neovascular age-related macular degeneration
NLRP3 inflammasome as therapeutic target in atrophic age-related macular degeneration
Dysregulation of Iron homeostasis-induced cellular inflammatory and neuro-degenerative processes in glaucoma
ITGA9 as a Novel Target to Activate Angiopoietin/TIE Signaling in Schlemm’s Canal
Investigating neuro-glial metabolic coupling in optic atrophies
Functions of the Aryl Hydrocarbon Receptor (AhR) in Corneal Tissue
Murine Single-cell Atlas of Corneal Disease
Investigation of the corneal phenotype of mice used in non-corneal studies of the SFB
Cross-Over Therapy strategies
The role of ZBP1 in the host immune response in Herpes Simplex Virus 1 (HSV-1) keratitis
CD83-related immunomodulation of retinal microglia in age-related macular degeneration
Integrated Transcriptomic Profiling of UVB-Induced DNA Damage, Inflammation, and Neovascularisation across Ocular Cell Populations
Therapeutic Protein Production Facility
Imaging Core Unit (ICU)
Central Tasks of the Collaborative Research Center
Integrated Research Training Group “Eye and Inflammation” (EI)
Data management, data mining and image analysis (“INF-Information Infrastructure Project”)
